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    Francis Lab
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Francis Lab

Using population-based epidemiology, molecular biology, and computational biology, the Francis lab focuses on understanding the etiology and genetics of brain tumors, among other cancers.

 

 

rat hippocampus
Development of a Glioma Liquid Biopsy

We take a multipronged approach that centers around leveraging extracellular vesicles and novel approaches to next generation sequencing combined with machine learning to identify molecular features that predict subtype and progression. 

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astrocytes
Immunity, viruses, genetics in cancer

A central thesis of our work is that the co-evolution of the human genome and infectious challenge has resulted in an evolutionary consequence that maximizes fitness at the cost of increasing complex disease risk. 

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