Helen Hansen
Helen Hansen manages the lab and biorepository for the UCSF Neuroepidemiology Laboratory, coordinating and executing epidemiological studies of glioma and pancreatic cancer. Our current projects focus on longitudinal studies of methylation derived immune profiles, utilizing archival specimens and contemporary material for highly multiplexed epigenetic profiling. Additional studies characterize extracellular vesicles using Next Generation Sequencing (NGS) and Tunable Resistive Pulse Sensing (TRPS) in these same, and newly acquired specimens. Past projects have included Genome Wide Association (GWAS), low density genotyping, sequencing, and expression studies of human cancers including glioma, pancreatic cancer, leukemia, meningioma, and lung cancer.
Other Interests: Gardening and Backpacking
2000: BA, Molecular and Cell Biology, University of California, Berkeley
Enrichment of a neutrophil-like monocyte transcriptional state in glioblastoma myeloid suppressor cells.
Wiencke JK, Nissen E, Koestler DC, Tamaki SJ, Tamaki CM, Hansen HM, Warrier G, Hadad S, McCoy L, Rice T, Clarke J, Taylor JW, Salas LA, Christensen BC, Kelsey KT, Butler R, Molinaro AM.
Res Sq [Preprint]. 2023 Dec 28:rs.3.rs-3793353. doi: 10.21203/rs.3.rs-3793353/v1
Inherited polymorphisms in the Human Leukocyte Antigen Region modify the association between varicella-zoster virus antibody reactivity and glioma prognosis.
Francis SS, Guerra G, Hansen HM, Wendt G, Kachuri L, Wiencke JK, Wrensch M.
Neuro Oncol. 2023 Oct 3;25(10):1910-1912. doi: 10.1093/neuonc/noad122.
Pre-surgery immune profiles of adult glioma patients.
Bracci PM, Rice T, Hansen HM, Francis SS, Lee S, McCoy LS, Shrestha PP, Warrier G, Clarke JL, Molinaro AM, Taylor JW, Wiencke JK, Wrensch MR.
J Neurooncol. 2022 Aug;159(1):103-115. doi: 10.1007/s11060-022-04047-y. Epub 2022 Jun 18.
Enhanced cell deconvolution of peripheral blood using DNA methylation for high-resolution immune profiling.
Salas LA, Zhang Z, Koestler DC, Butler RA, Hansen HM, Molinaro AM, Wiencke JK, Kelsey KT, Christensen BC.
Nat Commun. 2022 Feb 9;13(1):761. doi: 10.1038/s41467-021-27864-7.
Interactions of Age and Blood Immune Factors and Noninvasive Prediction of Glioma Survival.
Molinaro AM, Wiencke JK, Warrier G, Koestler DC, Chunduru P, Lee JY, Hansen HM, Lee S, Anguiano J, Rice T, Bracci PM, McCoy L, Salas LA, Christensen BC, Wrensch M, Kelsey KT, Taylor JW, Clarke JL.
J Natl Cancer Inst. 2022 Mar 8;114(3):446-457. doi: 10.1093/jnci/djab195.